Premier Hotels in Downtown Greenville

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Alan Reid

Updated: 14 March 2024 · 2 min

Nestled in the very heart of South Carolina, Greenville emerges as a radiant gem for travelers seeking both metropolitan vibrancy and quaint charm. Downtown Greenville, in particular, is lauded for its picturesque Main Street, brimming with life, cultural venues, and an array of dining options that promise to enchant every visitor. Amidst this bustling urban tapestry lie some of the most inviting accommodations, where staying at one of the hotels downtown becomes more than just a necessity—it transitions into a crucial part of the Greenville experience.

These downtown hotels not only provide a comfortable retreat after a day of exploration but also serve as gateways to discovering the essence of Greenville. With locations that put you steps away from the iconic Falls Park on the Reedy and the Peace Center, these hotels offer unmatched accessibility to the city’s top attractions. They stand as recommendations for those who seek to immerse themselves fully in Greenville's inviting atmosphere, melding luxurious comfort with the warmth of Southern hospitality.

Moreover, choosing to stay in the very heart of Greenville means you’re not just selecting a place to sleep; you're choosing an experience. Whether it’s the historic charm that entices you or the modern amenities and eco-friendly initiatives that many downtown hotels now feature, there’s an accommodation to meet every preference and need. Embarking on a journey to Greenville, particularly to its vivacious downtown area, promises an unforgettable encounter, with hotels that tantalize the senses and beckon travelers to return.
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Our Top 3

(Sorted by rating & number of reviews)

1. Holiday Inn Express Hotel & Suites Greenville, An Ihg Hotel
2. Super 8 By Wyndham Greenville
3. Quality Inn Greenville I-30

Luxurious Stays: Premier Greenville SC Hotels Downtown

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Greenville
Sep 16, 2025 - Sep 17, 2025

Holiday Inn Express Hotel & Suites Greenville, An Ihg Hotel

7.9

Good

(85 Reviews)

+ 72 photos
Holiday Inn Express Hotel & Suites in Greenville offers guests a blend of comfort and convenience at an affordable price. Known for its reliable service and welcoming atmosphere, this hotel features spacious rooms equipped with modern amenities. Guests can start their day with a complimentary breakfast, including hot and cold options, and stay connected with free Wi-Fi. The outdoor pool and fitness center provide perfect relaxation and workout solutions. Located just a short drive from downtown Greenville, guests have easy access to explore the city's attractions. This hotel represents an excellent choice for those looking for value without sacrificing quality during their stay in Greenville.
Address: 2901 Mustang Crossing
Rating: Good 7.9 (85 Reviews)
Rooms: 80
Price: From 105$

Luxurious Stays: Premier Greenville SC Hotels Downtown

Super 8 By Wyndham Greenville

5.8

Good

(84 Reviews)

+ 25 photos
For travelers looking for economical lodging without forgoing comfort, Super 8 by Wyndham Greenville offers an ideal solution. This hotel prides itself on providing clean, comfortable accommodations with complimentary breakfast and free Wi-Fi, ensuring a stay that is both affordable and pleasant. Its location allows for easy access to Greenville's business and cultural districts, making it convenient for guests looking to explore the city. The attentive staff and array of standard amenities make Super 8 by Wyndham a top choice for budget-conscious visitors seeking a fuss-free stay.
Address: 5010 Business Highway 69 South
Rating: Good 5.8 (84 Reviews)
Rooms: 52
Price: From 64$

Quality Inn Greenville I-30

5.7

Good

(186 Reviews)

+ 39 photos
Quality Inn Greenville I-30 is situated conveniently off the interstate, making it an excellent choice for travelers on the go. Offering guests comfortable rooms equipped with essential amenities, including a microwave and refrigerator in every room, the hotel ensures a relaxed and worry-free stay. Guests can enjoy a complimentary hot breakfast, free Wi-Fi, and access to an outdoor pool. Its proximity to key attractions and business centers in Greenville makes it a practical and appealing option for those looking for affordability without compromising on quality and location.
Address: 1209 East I-30
Rating: Good 5.7 (186 Reviews)
Rooms: 42
Price: From 69$